Symptoms of withdrawal typically begin within 24 hours after your last dose, and may last anywhere between a few days to a few weeks. A comedown is the letdown of high emotions following peak drug effects. Everyone metabolizes medications differently, so the half-life is different from person to person. If that happens, you may begin to notice it takes longer for you to feel the sedative effects of the drug, and the feelings may wear off more quickly. Most people will feel the strongest impacts from the drug for one to two hours. Most people will experience it between one and two hours after taking their dose.
What If You’re Using It To Treat An Anxiety Or Panic Disorder?

Doing so may help avoid withdrawal symptoms that can occur if you suddenly stop treatment. It’s not known whether it’s safe or effective to take Xanax for longer than 10 weeks for panic disorder. (Off-label use is when an FDA-approved drug is prescribed for a purpose other than what it’s approved for.) A taper is used to decrease your risk of withdrawal symptoms if your body has become physically dependent on Xanax.
RISKS AND PROPER USE
To learn about other mild side effects, talk with your doctor or pharmacist, or view Xanax’s prescribing information. The following lists contain some of the key side effects that may occur while taking Xanax. Xanax XR works over about 24 hours, so you’ll likely take a dose once per day.
What Drugs Interact With Alprazolam?
- Commonly used dosages are mentioned below, but always take the dosage your medical professional recommends.
- Depending on the disorder and the patient’s profile, the amount taken will differ.
- Xanax side effects can show up early in treatment or after a dose change.
- Cranstoun, a harm reduction charity in the Black Country, has produced guidance for people who take Xanax and other benzodiazepines, on how to do so safely.
- Xanax starts working about 30 minutes to 1 hour after taking a dose.
You can ask your doctor what other medications may be better options for you. Xanax may not be right for you if you have certain medical conditions or other factors affecting your health. Opioids are powerful drugs that are also known as opiates or narcotics. Due to these risks, doctors will typically not prescribe Xanax with an opioid unless no other treatment options are suitable.
The Food and Drug Administration (FDA) approves prescription drugs such as Xanax to treat certain conditions. If you have hangover-like symptoms when stopping Xanax treatment, talk with your doctor. A half-life chart can show you the amount of a dose that may still be in your system after a certain amount of time. If you need a pain reliever during Xanax treatment, ask your doctor or pharmacist to recommend a suitable medication. It’s important to note that some pain-relieving drugs contain acetaminophen in combination with an opioid.
Before you take Xanax, discuss your health history with your medical professional. If you have certain medical conditions or other factors that affect your health, Xanax may not be the right choice for you. Keep in mind that we haven’t listed all types of drugs that may interact with Xanax. This includes prescription and over-the-counter medication.
Interdose Symptoms

Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. It is against the law.Laboratory and/or medical tests (such as liver function tests) should be performed periodically to monitor your progress or check for side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

Taking Xanax With Other Drugs
Certain withdrawal symptoms may sometimes last for several weeks or months. You may be curious about how Xanax compares with other drugs that are prescribed for similar purposes, such as clonazepam. You may wonder how Xanax compares with other medications that are prescribed for similar purposes, such as Valium. Consuming alcohol during Xanax treatment can also increase your risk of an overdose from Xanax and, in rare cases, death.
What Does Xanax Feel Like? 11 Things To Know
- Combining Xanax (alprazolam) with therapy can help create a more well-rounded, holistic approach to effectively manage anxiety and panic disorders.
- The use of this drug may affect the health of the baby.
- (Off-label means using a drug for a condition it hasn’t been approved to treat.)
- Working with your healthcare team may help you stay on track with your treatment.
- By boosting the effect of GABA, Xanax helps reduce nervous tension and feelings of anxiety.
By that point, your body will eliminate half of the dose from your bloodstream. How long it takes for the drug to impact you will depend on several factors. However, the lingering effects or “fuzzy feelings” may stretch out for around six hours.

Xanax tablets are immediate release, which means all the medication is released as soon as the tablet dissolves. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. It is important to get rid of the medication as soon as you no longer need it or it is expired. This medication may cause harm and death if it is taken by other adults, children, or pets. Get rid of any unused medication after the expiration date. Misuse of this medication is dangerous and against the law.
What Is Alprazolam Prescribed For?
Panic attacks occur either unexpectedly or in certain situations (for example, driving), and can require higher dosages of alprazolam. It is believed that excessive activity in the brain may cause anxiety or other psychiatric disorders. Although your doctor is the best source for answering your specific questions about anxiety and treatment with XANAX, you can find answers to common questions here. You should always consult your doctor or another healthcare professional before taking any medication. Taking more than the recommended dosage of Xanax can lead to serious side effects and, in rare cases, death.
Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks. Alprazolam is used in the management of anxiety disorders and nausea due to chemotherapy. In 2023, it was the 37th most commonly prescribed medication in the United States, with more than 15 million prescriptions.
Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. It’s always best to start with a low dose and gauge how you respond to this medication before consulting with your health care provider to increase your dosage, adds Dr. Dimitriu. As the medicine’s effects rapidly end, anxiety returns and some people are left wanting more,” he says, advising patients to take as little as they can and to space out doses as much as possible. Therefore, in order to treat the underlying anxiety symptoms, it’s important to receive evidence-supported psychological treatment, such as cognitive behavioral therapy or somatic experiencing therapy. Xanax (also called alprazolam) is one of the most well-known anti-anxiety medications, says Alex Dimitriu, M.D., a double board-certified physician in psychiatry and sleep medicine and founder of Menlo Park Psychiatry & Sleep Medicine and BrainfoodMD.

ALPRAZOLAM (al PRAY zoe lam) treats anxiety. Cleveland Clinic is a non-profit academic medical center. You may report side effects to the FDA at FDA-1088.
Alprazolam and other benzodiazepines may also cause the development of physical dependence, tolerance, and benzodiazepine withdrawal symptoms during rapid dose reduction or cessation of therapy after long-term treatment. Recurrence of symptoms such as anxiety may simply indicate that the drug was having its expected anti-anxiety effect and that, in the absence of the drug, the symptom has returned to pretreatment levels. Withdrawal and rebound symptoms commonly occur and necessitate a gradual reduction in dosage to minimize withdrawal effects when discontinuing.